Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Purpose

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.

Condition

  • Sickle Cell Trait

Eligibility

Eligible Ages
Between 18 Years and 65 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  1. Are willing to voluntarily participate and sign the study consent 2. Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status 3. Be willing and able to participate in the 2- year study plan. 4. Adults ages 18-65

Exclusion Criteria

  1. Unwilling to sign consent 2. Known end-stage renal disease or dialysis 3. Known SCD (including sickle cell-beta thalassemia) 4. People who do not have SCT

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Individuals with sickle cell trait
  • Other: Biologic Specimen Collection
    Participants will have blood and urine collected annually at Baseline, Year 1 and Year 2.

Recruiting Locations

University of Alabama
Birmingham, Alabama 35294
Contact:
Lauren Mullis
lmullis@uabmc.edu

More Details

Status
Recruiting
Sponsor
National Alliance for Sickle Cell Centers

Study Contact

Julie Kanter, MD
(202) 596-1548
jkanter@sicklecellcenters.org