Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

Purpose

The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid

Condition

  • Shoulder Arthroplasty

Eligibility

Eligible Ages
Between 18 Years and 79 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Skeletally mature patients (ages 18-79) undergoing primary total shoulder arthroplasty

Exclusion Criteria

  • Patients with Cancer, venous thromboembolism, stroke, heart disease, pregnant or nursing, allergic to TXA, current tobacco use, anticoagulants other than aspirin.

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Triple (Participant, Care Provider, Investigator)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
oral tranexamic acid
  • Drug: oral tranexamic acid
    one group of subjects will receive oral tranexamic acid and the other will receive oral placebo
Placebo Comparator
Oral Placebo
  • Drug: Placebo
    one group of randomized subjects will receive placebo and the other will receive oral tranexamic acid

Recruiting Locations

University of Alabama at Birmingham
Birmingham, Alabama 35205
Contact:
Walter Smith
205-930-8554
waltersmith@uabmc.edu

More Details

Status
Recruiting
Sponsor
University of Alabama at Birmingham

Study Contact

Walter Smith
205-930-8554
waltersmith@uabmc.edu