Early Time-Restricted Eating in Older Adults With Hypertension

Purpose

The purpose of this study is to find out how early time-restricted eating affects body rhythms and improves cardiometabolic health in older adults.

Conditions

  • Hypertension
  • Eating Behaviors

Eligibility

Eligible Ages
Over 60 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Consent to participate in the study - Men and women ≥ 60 years old - Average office systolic BP ≥130 mmHg - Self-reported ≥12 hours eating period per day of at least 5 days/week - Stable health history over the past 2 months

Exclusion Criteria

  • Fasting >12 hours per day - Actively trying to lose weight by participating in formal weight loss program or significantly restricting calorie intake - Have lost ≥ 10 pounds in last 3 months - Unable to wake up at a regular time between 6-8 am - Perform overnight shift work more than 1day/week on average - Resting heart rate of >120 beats per minute, systolic blood pressure > 180 mmHg and/or diastolic blood pressure of > 100 mmHg - Have been diagnosed with diabetes - On insulin or diabetes medication - Unstable angina, heart attack or stroke in the past 3 months - Continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure - Pregnant or breastfeeding - Rheumatoid arthritis, Parkinson's disease or currently on dialysis - Current diagnosis of a major psychiatric condition that would impair study participation - Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease - Active treatment for cancer in the past year - Taking medications that preclude fasting for 16 hours (e.g. must be taken with food at least 12 hours apart)

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Intervention 		Early time-restricted eating
  • Behavioral: Early time-restricted eating
    The participants will be asked to fast for a target of 16 hours per day (eat ad libitum within the 8-hour eating window, starting between 6:30-8:30 am), 6 days/week for 12 weeks. Participants will be allowed to consume calorie-free beverages, sugar-free gum, and will be encouraged to drink plenty of water throughout the entire intervention period.
No Intervention
Control

Recruiting Locations

University of Alabama at Birmingham
Birmingham, Alabama 35294
Contact:
Yi Lin, PhD
205-996-5876
yilin@uabmc.edu

More Details

Status
Recruiting
Sponsor
University of Alabama at Birmingham

Study Contact