Early Time-Restricted Eating in Older Adults With Hypertension

Purpose

The purpose of this study is to find out how early time-restricted eating affects body rhythms and improves cardiometabolic health in older adults.

Conditions

  • Hypertension
  • Eating Behaviors

Eligibility

Eligible Ages
Over 60 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Consent to participate in the study - Men and women ≥ 60 years old - Average office systolic BP ≥130 mmHg - Self-reported ≥12 hours eating period per day of at least 5 days/week - Stable health history over the past 2 months

Exclusion Criteria

  • Fasting >12 hours per day - Actively trying to lose weight by participating in formal weight loss program or significantly restricting calorie intake - Have lost ≥ 10 pounds in last 3 months - Unable to wake up at a regular time between 6-8 am - Perform overnight shift work more than 1day/week on average - Resting heart rate of >120 beats per minute, systolic blood pressure > 180 mmHg and/or diastolic blood pressure of > 100 mmHg - Have been diagnosed with diabetes - On insulin or diabetes medication - Unstable angina, heart attack or stroke in the past 3 months - Continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure - Pregnant or breastfeeding - Rheumatoid arthritis, Parkinson's disease or currently on dialysis - Current diagnosis of a major psychiatric condition that would impair study participation - Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease - Active treatment for cancer in the past year - Taking medications that preclude fasting for 16 hours (e.g. must be taken with food at least 12 hours apart)

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Intervention 		Early time-restricted eating
  • Behavioral: Early time-restricted eating
    The participants will be asked to fast for a target of 16 hours per day (eat ad libitum within the 8-hour eating window, starting between 6:30-8:30 am), 6 days/week for 12 weeks. Participants will be allowed to consume calorie-free beverages, sugar-free gum, and will be encouraged to drink plenty of water throughout the entire intervention period.
No Intervention
Control

Recruiting Locations

University of Alabama at Birmingham
Birmingham 4049979, Alabama 4829764 35294
Contact:
Yi Lin, PhD
205-996-5876
yilin@uabmc.edu

More Details

Status
Recruiting
Sponsor
University of Alabama at Birmingham

Study Contact