Purpose

The goal of this clinical trial is to compare two types of surgical fixation in patients with specific kinds of distal femur fractures. The main questions it aims to answer is which operation for distal femur fractures is better for efficient return to work and everyday activities.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age greater than or equal to 18 years - Surgically treated displaced distal femur extra articular or complete articular fractures

Exclusion Criteria

  • Patients with injury features that preclude treatment with 2 implants - Patients unlikely to follow-up due to homelessness, or planning follow up at another institution - Body Mass Index (BMI) > 40 - Injury due to ground level fall - Patient that speaks neither English or Spanish - Patients with multisystem injuries that could preclude return to work - < 18 years of age - Prisoner

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
adult patients with extra-articular or complete articular distal femur fractures that will be operatively treated recruited from one of the participating sites during the index hospitalization
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Other
Single Implant Fixation
Single implant fixation with either a precontoured lateral locking plate or an intramedullary nail.
  • Procedure: Single Implant Fixation
    Single implant fixation with either a precontoured lateral locking plate or an intramedullary nail.
Other
Dual Implant Fixation
Dual implant fixation with either a lateral locking plate plus an intramedullary nail or a lateral locking plate plus a supplemental medial plate.
  • Procedure: Dual Implant Fixation
    Dual implant fixation with either a lateral locking plate plus an intramedullary nail or a lateral locking plate plus a supplemental medial plate.

Recruiting Locations

University of Alabama Birmingham
Birmingham 4049979, Alabama 4829764 35233
Contact:
Clay Spitler, MD
caspitler@uabmc.edu

More Details

Status
Recruiting
Sponsor
Wake Forest University Health Sciences

Study Contact

Rachel Seymour, PhD
704.355.2000
Rachel.Seymour@atriumhealth.org

Detailed Description

Fractures of the distal femur are severe and common injuries sustained by Wounded Warriors in combat. Despite advances in implant technology, these injuries continue to have an unacceptably high rate of nonunion (failure to heal) of approximately 20%. This adverse outcome requires additional surgery to achieve fracture healing, which prolongs recovery and further delays return to duty often beyond one year after injury. The goal of this study is to investigate a potential treatment for distal femur fractures that has the potential to improve the likelihood of fracture healing and accelerate return of patient function during the healing process.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.