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Purpose

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Conditions

Eligibility

Eligible Ages
Between 19 Years and 99 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Clinical diagnosis of psoriasis - Must be age 19 or older. - Must be Fitzpatrick skin type I, II, III, IV, V, VI.

Exclusion Criteria

  • Subjects who do not have photosensitive disease and are not on photosensitizing medications. - Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy). - Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants. - Subjects who are pregnant.

Study Design

Phase
Study Type
Observational
Observational Model
Case-Control
Time Perspective
Cross-Sectional

Recruiting Locations

The Kirklin Clinic
Birmingham, Alabama 35294
Contact:
Wendy Cantrell
205-502-9960
wcantrell@uabmc.edu

More Details

Status
Recruiting
Sponsor
University of Alabama at Birmingham

Study Contact

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.